The extemporaneous formulation of 20% Aluminum chloride in a 4% Salicylic Aacid Gel Base

Ingredients Weight           Compounding steps

Aluminum Chloride hexahydrate

20g

1.     Grind 20 grams of aluminum chloride hexahydrate in a mortar until a fine powder is obtained.

2.     Mix this powder with 10 ml of absolute ethanol and grind more.

3.  Add the former mixture slowly (i.e. over  a 10 minutes period) to SAGB, grinding all the way through with each addition.

4.  Keep this formulation refrigerated.

Absolute ethanol

10ml
Salicylic acid gel 100g

 

 

The extemporaneous formulation of 4% Salicylic Acid Gel Base

Ingredients Weight Compounding steps
Salicylic Acid USP

4g

1.     SA Salicylic Acid / ethanol: dissolve 4 grams of  Salicylic Acid in 5-10 ml of absolute ethanol.

2.     Propylene glycol - hydroxy propyl cellulose mixture.

a.     Dampen 3.0 g of hydroxy propyl cellulose 1500 CPS powder with propylene glycol and mix until the combination  becomes a paste.

b.     Add the balance of propylene glycol slowly to the paste to have a total weight of approximately 63 g of a lump free mixture.        

3.    Mix the Salicylic Acid  / ethanol with Propylene glycol - hydroxy propyl cellulose mixture and add absolute alcohol to have a final weight of 100g.
Propylene glycol

60g

Hydroxypropylcellulose 1500 CPS

3g

Absolute ethanol qs ad

100g